Comera Life Sciences Holdings, Inc.
12 Gill Street, Suite 4650
Woburn, Massachusetts 01801
February 8, 2023
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Comera Life Sciences Holdings, Inc. |
| Registration Statement on Form S-1 |
| File No. 333-269564 |
| Request for Acceleration |
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Comera Life Sciences Holdings, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-1, as amended (File No. 333-269564) so that it may become effective at 4:00 p.m. Eastern time on February 10, 2023, or as soon thereafter as practicable.
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| Very truly yours, | ||
| Comera Life Sciences Holdings, Inc. | ||
| By: | /s/ Jeffrey S. Hackman | |
| Name: |
Jeffrey S. Hackman | |
| Title: |
Chairman, President and CEO | |